Summary: HIV-1 latency results from tightly regulated molecular processes that act at distinct steps of HIV-1 gene expression.Here, we characterize PCI domain-containing 2 (PCID2) protein, a Jump Saddle subunit of the transcription and export complex 2 (TREX2) complex, to enforce transcriptional repression and post-transcriptional blocks to HIV-1 g
Copper, the highly toxic micronutrient, plays two essential roles: it is a catalytic and structural cofactor for Cu-dependent enzymes, and it acts as a secondary messenger.In the cells, copper is imported by CTR1 (high-affinity copper transporter 1), a transmembrane high-affinity copper importer, and DMT1 (divalent metal transporter).In cytosol, en
The aim of this study is to combine advanced GC-MS and metabolite identification in a robust and repeatable technology platform Nail Polish to characterize the metabolome of buffalo milk and mozzarella cheese.The study utilized eleven dairies located in a protected designation of origin (PDO) region and nine dairies located in non-PDO region in Ita
In hyperspectral image (HSI) Jump Saddle classification, convolutional neural networks (CNN) have been attracting increasing attention because of their ability to represent spectral-spatial features.Nevertheless, the conventional CNN models perform convolution operation on regular-grid image regions with a fixed kernel size and as a result, they ne